HiTSeq 2026

Keynote speakers

Andre Kahles
Andre Kahles
Senior Scientist
ETH Zürich, Switzerland
Christopher E. Mason
Christopher E. Mason
Professor
Weill Cornell Medicine, USA
Mihaela Pertea
Mihaela Pertea
Associate Professor
Johns Hopkins University, USA


Monday, July 13, 2026

All times listed are in EST, Room: International Ballroom Center

11:00-11:05 Welcome
11:05-12:00 Keynote: From Reads to Retrieval: Petabase-Scale Sequence Search with MetaGraph
Andre Kahles
12:00-12:20 Proceedings Presentation: Scalable computation of ultrabubbles in pangenomes by orienting bidirected graphs
Juha Harviainen, Francisco Sena, Corentin Moumard, Aleksandr Politov, Sebastian Schmidt, Alexandru I. Tomescu
12:20-12:40 Proceedings Presentation: RLBWT-Based LCP Computation in Compressed Space for Terabase-Scale Pangenome Analysis
Ahsan Sanaullah, Nathaniel Brown, Pramesh Shakya, Arun Deegutla, Ardalan Naseri, Benjamin Langmead, Degui Zhi, Shaojie Zhang
12:40-13:00 ImpuT2T: Pangenome-Based Patching for Human Genome Assemblies
Mao-Jan Lin, Vikram Shivakumar, Ben Langmead
14:20-14:40 Proceedings Presentation: Optimizing sparse and skew hashing: faster k-mer dictionaries
Giulio Ermanno Pibiri, Rob Patro
14:40-15:00 10-minimizers: a promising class of constant-space minimizers
Arseny Shur, Ido Tziony, Yaron Orenstein
15:00-15:20 The gift of novelty: repeat-robust k-mer-based estimators of mutation rates
Haonan Wu, Paul Medvedev
15:20-15:40 Proceedings Presentation: Incorporating indel channels into average-case analysis of seed-chain-extend
Spencer Gibson, Yun William Yu
15:40-16:00 ORION: A High-Performance Barcode and UMI Correction Tool for Oxford Nanopore Single-Cell Sequencing
Dohun Yi, Jin-Wu Nam
16:20-16:40 SpatiaXen: An Open-Source Interactive Platform for Cell-Type-Resolved Spatial Transcriptomics Analysis
Anirban Chakraborty, Cort Thompson, Lauren Wade-Kleyn, Mark Reimers, Erin Purcell
16:40-17:00 Proceedings Presentation: Detecting and reconstructing breakage-fusion-bridge cycles from long-read sequencing using BFBArchitect
Chaohui Li, Siavash Raeisi Dehkordi, Daniel Muliaditan, Ramanuj Dasgupta, Jens Luebeck, Kaiyuan Zhu, Vineet Bafna
17:00-18:00 Keynote: Genetic and epigenetic engineering and technologies to prepare for deep space
Christopher Mason

Tuesday, July 14, 2026

All times listed are in EST, Room: International Ballroom Center

11:00-12:00 Keynote: From Reads to Transcripts to Biological Insight
Mihaela Pertea
12:00-12:20 scVarSim: A Unified Simulator for Benchmarking Genetic Variant Calling and RNA Editing Detection in Single-Cell RNA-seq Data
Weijian Wang, Jingyi Jessica Li
12:20-12:40 Spatiotemporal cell type deconvolution leveraging tissue structure
Macrina Lobo, Ziqi Zhang, Xiuwei Zhang
12:40-13:00 MethylSeg: Context-Aware Methylome Segmentation Enables Robust PMD Detection in Array and WGBS Data
Jacob Tye, Kendell Clement
14:20-14:40 Amaranth: Enhanced Single-Cell Transcript Assembly via Discriminative Modeling of UMI Reads and Internal Reads
Xiaofei Carl Zang, Tasfia Zahin, Irtesam Mahmud Khan, Qian Shi, Yi Xing, Mingfu Shao
14:40-15:00 Minerva: Breakpoint-Guided Allele-Specific Copy Number Inference in Long-Read Cancer Genomes
Ayse Keskus, Tanveer Ahmad, Isabel Rodriguez, Anton Goretsky, Ataberk Donmez, Sonam Tulsyan, Nicholas Syracuse, Michael Dean, Mikhail Kolmogorov
15:00-15:20 Unravelling genome-wide mosaic microsatellite mutations at single-cell resolution
Yanmei Dou
15:20-15:40 SQANTI-epi: Functional and Quality Annotation of Single-Molecule Epigenomic Data
Tianyuan Liu, Ana Conesa
15:40-16:00 Proceedings Presentation: Likelihood-based optimization enables accurate copy number estimation for paralogous genes using exome data
Sang Yoon Byun, Vikas Bansal
16:40-17:00 Proceedings Presentation: Seqwin: Ultrafast identification of signature sequences in microbial genomes
Michael X. Wang, Bryce Kille, Michael G. Nute, Siyi Zhou, Lauren B. Stadler, Todd J. Treangen
17:00-17:20 Proceedings Presentation: pHapCompass: Probabilistic Assembly and Uncertainty Quantification of Polyploid Haplotype Phase
Marjan Hosseini, Ella Veiner, Thomas Bergendahl, Tala Yasenpoor, Zane Smith, Margaret Staton, Derek Aguiar
17:20-17:40 Pilot discovery of allele-specific modification QTLs from long-read RNA sequencing
Michael Goneos, Theodore Nelson, Christopher Mason
17:40-18:00 CRANE: Correcting Errors in Raw Nanopore Signals Using Hidden Markov Models
Simon Ambrozak, Ulysse McConnell, Bhargav Srinivasan, Burak Ozkan, Ernest Zhang, Can Firtina